Each show can be watched from first to last episode, to maximize your binge-watching potential.
There are few shows out there that have a sense of humor as unique as Scrubs. Between JD's fantasies, Dr. Cox's wordplay, the almost IRL-Looney-Tunes emphasis on physical comedy, and the wild card that is Neil Flynn's Janitor, there's something for everyone.
Louis C.K. has moved on to new shows (like Horace and Pete, which is available on his website), so every episode of his first FX series is now available on Netflix. It's brilliantly done, often strange, and at times insanely funny. It's unclear whether Louis meant for his character to be as problematic toward women as he turned out to be later on in the series, but the show is worth a watch regardless.
Britain has put out some exceptional crime shows in the past (Luther would be included on this list, but not every episode is available on Netflix as of yet), but Top Boy is one of the best. Focusing on London street gangs, the show is perfect for those who enjoyed The Wire or The Sopranos and want a little more well-made crime drama in their lives.
This might seem like an obvious choice, but there are a lot of episodes of Friends, and if you weren't quite old enough in the '90s or early '00s, there's a good chance you haven't really experienced the whole show. But even if you have, go back and give it all a watch again. You'll be glad you did.